National Health Laboratory Service
|Consultant-in-charge||Routine C17 lab||Dr Jessica Opie||Tel: 404-3082||Fax: 404-4105|
|Consultant-in-charge||Red Cross Hospital lab||Dr Lee Ann Phillips||Tel: 658-5228||Fax: 658-5206|
|Lab Manager||NHLS Path labs||Dr Lucille Human||Tel: 404-4186||Fax: 404-5281|
|Lab Manager (C17)||Haematology||Mrs Delmaine Rousseau||Tel: 404-4136||Fax: 404-4105|
|Lab Manager (RXH)||Haematology||Zulfa Abrahams||Tel: 658-5142||Fax: 658-5206|
|Consultant||Haematology||Dr Emil Beltchev||Tel: 404-3081||Fax: 404-4105|
|Consultant||Haematology||Dr Mona Lisa Ntobongwana||Tel: 404-4244|
|Consultant||Haematology||Dr Nomusa Mashigo|
|Medical Scientist||Molecular Biology lab C21||Dr Karen Shires||Tel: 406-6673|
- Routine diagnostic laboratory (C17 - Groote Schuur Hospital)
- Molecular Laboratory (C21 - Groote Schuur Hospital)
- Routine diagnostic laboratory (Red Cross Children's Hospital)
The C17/GSH Haematology Laboratory offers a combined Routine and Emergency (24 hours a day STAT) diagnostic service to Groote Schuur Hospital, as well as to some peripheral hospitals such as Mowbray Maternity, Victoria Hospital and False Bay Hospitals. This includes testing of full blood counts and differentials as well routine coagulation testing.
The Antenatal Laboratory also tests haemoglobins and antibody testing for numerous of the MOU's in the Cape Peninsula as well as the Western Cape. As part of the ARV treatment program, CD4 flow cytometry also forms part of the routine testing.
Many of the specialised tests that we offer are not performed in regional laboratories, so samples are received from both Western Cape and Eastern Cape Hospitals and Clinics plus a number of private facilities for:
- Bone marrow biopsies for the diagnosis and management of numerous haematological malignancies as well as RVD patients to investigate for disseminated TB or other infiltrations
- Flow cytometry which is used to classify leukemias and lymphomas as part of either the diagnostic workup or management of the patient during treatment
- Testing of patients with Haemophilia
- Testing of patients for haemoglobinopathies
- Molecular testing by PCR is offered for a number of haematological diseases including Chronic Myeloid Leukaemia (BCR-ABL), other myeloproliferative Disorders (JAK2) and Acute Promyelocytic Leukaemia (PML-RARA). Further tests are regularly becoming available.
Cytogenetics and FISH
Molecular testing by PCR is offered for a number of haematological diseases including Chronic Myeloid Leukaemia (BCR-ABL), other myeloproliferative Disorders (JAK2) and Acute Promyelocytic Leukaemia (PML-RARA). Further tests are regularly becoming available.
Molecular tests currently on offer:
|JAK2V617F||Chronic Myeloproliferative Disorder (Ph negative) confirmatory test|
|BCR/ABL p190 and p210 qualitative assay||Diagnostic Chronic Myeloid Leukemia (CML) assay|
|BCR/ABL p210 quantitative assay||Monitoring of CML patients|
|ABL kinase mutation detection assay||Assessment of treatment resistance mutations in CML patients|
|PML/Raralpha detection assay||Diagnosis and monitoring disease in Acute Promyelocytic leukemia (APL) patients|
|FLT3 ITD detection assay||Prognostic assay for Acute Myeloid Leukemia patients with normal cytogenetics|
|Factor V leiden/Prothrombin/MTHFR point mutation assay||Inherited Thrombosis risk factors|
Haematology Routine Diagnostic Laboratory :
Red Cross Children's Hospital UCT/NHLS Division of Haematology provides a 24 hour paediatric routine and specialized academic haematology service to the Red Cross and Mowbray Maternity Hospitals in Cape Town. It is particularly geared for processing small sample volumes. The unit specialises in the diagnosis and management of a wide range of haematological disorders in children. The laboratory provides a full diagnostic service for leukaemia, including bone marrow biopsies, cytochemistry, immunophenotyping and cytogenetic and molecular analysis.Â A full spectrum of haemolytic and coagulation assays are performed for both congenital and acquired disorders. Furthermore, the laboratory receives many referred samples both from other NHLS centres and from private practice pathologists.Â The laboratory provides a comprehensive diagnostic and consultation service to clinicians regarding paediatric diseases.
Contact us at:
Institute of Child Health Building:Â Ground Floor
Red Cross Children's Hospital
Tel: 021 658 5203/4/5
Fax: 021 658 5206
The Haematology Laboratory, is part of the co-operative that offers a Clinical Trials service both to the Pharmaceutical companies and to Clinicians performing academic studies.
For further information, please contact:
Chemical Pathology Clinical Trials Manager, Dr Heleen Vreede